51. In Raynaud\'s phenomenon the digits (fingers and toes) become ischemic (lack

Question

51. In Raynaud's phenomenon the digits (fingers and toes) become ischemic (lack blood) after exposure to cold or with emotional stress. The condition is due to excessive sympathetic stimulation of smooth muscle in the arterioles of the digits and a heightened response to stimuli that cause vasoconstriction What receptors based on the symptoms above is involved in the phenomenon? Justify your answers. a. b. What therapeutic measures do you suggest based on what you have learned? What brought you to this conclusion? Do you expect adverse effects? If so, what effects do you imagine and why would they occur? c.

Explanation / Answer

However, the process of Raynaud's phenomenon is still not fully known but the most concerning receptors in this phenomenon is Alpha- 2C-adrenoreceptor. For this phenomenon, we suggest to use gloves and avoiding of open touch. We consider using of Air conditioners. In case of quick treatment, we use calcium blockers like nifedipine that regulates vasodilations. The other therapies are behavioral and educational therapy, which encompass studies of precautions. The adverse effects include headache, ankle swellings, flushings and retardations.

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