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Part C Do you think contraction would resume if ATP were added to the flask cont

ID: 255227 • Letter: P

Question

Part C Do you think contraction would resume if ATP were added to the flask containing the AMPPNP-arrested myofibrils? Explain Yes, AMPPNP is a noncompetitive inhibitor of the ATPase and should be displaced from the binding site at any intracellular ATP concentration Yes, AMPPNP is a competitive inhibitor of the ATPase and should be displaced from the binding site if the intracellular ATP concentration is elevated to a high enough level. No, AMPPNP is a noncompetitive inhibitor of the ATPase and should not be displaced from the binding site even if the intracellular ATP concentration is elevated to a high enough level. No, AMPPNP is a competitive inhibitor of the ATPase and should not be displaced from the binding site even if the intracellular ATP concentration is elevated to a high enough level Submit Request Answer

Explanation / Answer

AMP-PNP is a structural analogue of ATP which menas they are structuraly similar. if a compound is structuraly similar it acts as a competitive inhibitor as it binds to the exact active site of the enzyme where the original molecule whould bind. therefor by increasing the ATP concentration, the availability of it increases and there is a higher chance that AMP-PNP can be replaced from the active site. with higher ATP concentration competitiveness of AMP-PNP is reduced.

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