1) Describe the forces that drive and stabilize proteirn folding. Start your des
ID: 254244 • Letter: 1
Question
1) Describe the forces that drive and stabilize proteirn folding. Start your description with the initial exposure of the polypeptide from the ribosome to its new water-based environment (the cytosol) and continue through the final stable structure including the formation of secondary and tertiary protein structures 2) Describe one of the three cell signaling cascades presented in class starting from an extracellular signaling molecule outside the cell and ending in a change in gene expression. Include in your description any and all allosteric events that take place describing their effects on each protein's activity. Use specific names of signaling molecules and proteins wherever possible.Explanation / Answer
1). There are two biochemical models (The diffusion-collision model and the nulceation-condensation model) of protein folding developed over time as the biochemical research is profoundly going on in the field of biochemistry. This development in protein folding research has enabled various biochemists to unravel the exact stability of the protein during its maturation in the endoplasmic reticulum. The fast kinetics of experimental Levinthal paradox & nucleation-condensation model has illustrated that the initial short stretches of helix-helix loop formation in secondary structure are faster stage followed by formation of molten globule with stabilized intramolecular hydrogen bonding along with disulfide bridges. This is followed by formation of three-dimensional protein structure.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.