Depurination of purine bases results in an apurinic site. Assume a single depuri
ID: 253960 • Letter: D
Question
Depurination of purine bases results in an apurinic site. Assume a single depurination event occurs in the GC base pair of the sequence below and is not repaired. Then, if two rounds of replication occur, which of the following DNA sequences will exist after two rounds of replication? Remember that when DNA polymerases encounter an apurinic site, most often an A is incorporated into the newly synthesized strand. Assume this is true for the sequence below.
...TACT...
...ATGA...
Select one or more:
...TACT...
...ATGA...
...TAAT...
...ATTA...
...TAGT...
...ATCA...
...TA_T...
...ATAA...
...TATT...
...ATAA...
...TAAT...
...AT_A...
Explanation / Answer
Answer after two round of replication, as in depurination purine (A or G) is removed and placed by A is incorporated in apurinic site so G is replaced by A. So the given sequence will exist
...TATT...
...TAAT...
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