ork 2O-For Credit instructions I help Question 20 (of 25) H Save & Exit Submlt v

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ork 2O-For Credit instructions I help Question 20 (of 25) H Save & Exit Submlt value: 0.80 points p53 mutations Estimates are that p53 is mutated in 50% of all human cancers. If the gene that encodes p53 is mutated such that p53 is non-functional, what processes would be affected? Check all that apply. The ability to halt the cell cycle in response to DNA damage. The ability to halt the cell cycle in response to the chromosomes not properly aligning on the metaphase plate. The ability to repair DNA damage. The ability to activate Cdks. The ability to stimulate cell death processes if the cell is irreparably dameged References eBook&Resources; Check All That Apply p53 mutations Section 10.07 Cancer is a Foure of Cel Cycle Controi

Explanation / Answer

Answer: The following statements in the given options are correct.

The ability to halt the cell cycle in response to DNA damage.

The ability to repair DNA damage.

The ability to stimulate cell death processes if the cell is irreparably

Explanation:

p53 has many mechanisms of anticancer function and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. In its anti-cancer role, p53 works through several mechanisms:

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