1. Which of the following statements is true regarding factors associated with t
ID: 252982 • Letter: 1
Question
1. Which of the following statements is true regarding factors associated with the immortalization of cancer cells? A) inhibition of growth B) stimulation of apoptosis C) telomerase activity D) tumor-suppressor activation E) both choices B and D 2. The most frequently encountered category of cancer is A) carcinoma. B) sarcoma. C) lymphoma. D) leukemia. E) both choices C and D 3. All of the following are ways cancer cells avoid growth and invasion restriction imposed by the immune system except A) they are heterogeneous groups of cells. B) cancer cells often respond to density-dependent growth factors. C) some cancer cells produce leukotoxins. D) some cancers often "hide" in dense supporting tissue E) some cancers produce low levels of surface antigens. 4. The presence of- in the microenvironment of cancer cells acts a potent inhibitor of cell proliferation. A) IL-1 B) TGF-beta C) TNF-alpha D) IL-2 E) INF-gamma 5. PAHs (polycyclic aromatic hydrocarbons) found in tobacco smoke preferentially bind to regions within the and trigger base substitutions. A) GAL-4 gene B) p53 gene C) DMBA gene D) homeogenes ) viral geneExplanation / Answer
1) The correct option is C. telomerase activity.
Telomerase activity is associated with the immortalization of cancer cells.
2) The correct option is A. carcinoma.
Carcinoma is a type of cancer, which starts in cells and make up the skin or the tissue lining organs. Cancer cells are abnormal cells, which divide without control.
3) The correct option is B) cancer cells often respond to density-dependent growth factors.
All of the following are ways cancer cells avoid growth and invasion restriction imposed by the immune system except cancer cells often respond to density-dependent growth factors.
4) The correct option is B) TGF-beta.
The presence of TGF-beta in the microenvironment of cancer cells. It acts as a potent inhibitor of cell proliferation. TGF-beta is a multifunctional cytokine that includes four different isoforms and many other signaling proteins produced by all white blood cell lineages.
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