3. Multiple Alleles and Codominance (ABO Blood Types) Blood tyoing is often used

Question

3. Multiple Alleles and Codominance (ABO Blood Types) Blood tyoing is often used as forensic evidence in trials. In one such trial, a woman who was type O has a baby that is also type O, and she is claiming that a man of blood type AB is the father of the child. If you were on the what conclusion would you make regarding this accusation? Show your evidence in a Punnet square and Rh factors are the result of another, unlinked allele where the gene for the factor (D) is dominant to being negative and not having the factor (d). Mother-fetus incompatibility occurs when the mother is Rh- and her fetus is Rh+, Maternal antibodies can cross the placenta and destroy fetal red blood cells. Rh blood type incompatibility is still the leading cause of potentially fatal blood related problems of the newborn, so it used to be a serious concern before the Rho-GAM serum was produced. Rh type mother-fetus incompatibility occurs only when an Rh+ man fathers a child with an Rh- mother. Since an Rh+ father can have either a DD or Dd genotype, there are 2 mating combinations possible with differing risks as shown below. Regardless of the father's genotype, if he is Rh+ and the mother is Rh., doctors assume that there will be an incompatibility problem and act accordingly Indicate the possible phenotypes from mating a woman with type O, Rh with a man with type A, Rh+ The man is homozygous for type A and heterozygous for Rh factor a. b. What is the chance that there may be complications due to fotal incompatibility due to the Rh factor?

Explanation / Answer

Answer:

3). Blood type O baby is not possible with father, who has type AB blood.

Woman with type O blood (ii) x Man with type AB blood (IAIB)-----Parents

IA

IB

i

IAi (type A)

IBi (type B)

                     

4a).

Woman type O, Rh- x Man with type A, Rh+

                       ii ; dd x IAIA ; Dd ---------------------Parents

IA D

IA d

i d

IAi ; Dd (blood type A, Rh+)

IAi ; dd (blood type A, Rh-)

4b).

50% of the children are with complications due to fetal incompatability and their genotype is IAi ; Dd

IA

IB

i

IAi (type A)

IBi (type B)

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