3 34. You ingest an antibiotic that inhibits bacterial topoisomerase. What effec
ID: 252129 • Letter: 3
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3 34. You ingest an antibiotic that inhibits bacterial topoisomerase. What effect will most likely have on the bacteria? a. It can't synthesize primers It can't remove supercoils during DNA replication c. It can't link Okazaki fragments d. It can't perform transcription e. It can't perform translation 35. DNA replication is described as being bidirectional. What does this term re a. Both replication forks move in opposite directions b. DNA polymerase can add nucleotides to the 5 and the 3' end of a primer c. DNA polymerase can move in two d forth as it is being replicated The DNA molecule moves back and forth as it is being replicated It means the same as the term semiconservative replication e. 36. What is the difference between the leading and lagging strands during DNA replication? a The leading strand is synthesized continuously in the 5' to 3' direction while the lagging strand is synthesized discontinuously in 5' to 3" The leading strand is synthesized discontinuously in the 3' to 5' direction while the lagging strand is synthesized continuously in 5' to 3' b. c. The leading strand requires an RNA primer whereas the lagging strand does not d. There are different DNA polymerases involved in elongation of the leading and lagging strands Where does DNA replication begin on the chromosome? a. the promoter b. the origin of replication c. the origin of transcription d. the start codon the ribosomal binding siteExplanation / Answer
34. The answer is b. It can't remove supercoils during DNA replication.
As the helicase unwinds the DNA stands, the supercoils forms. To remove the stress on DNA from these supercoils, the DNA topoisomease cleaves the strands and relaxes the DNA, otherwise due to stree it leads to DNA damage and DNA replication inhihits.
35. The answer is a. Both relication forks move in opposite direction.
When the replciation initiates at origin of replication, the replication fork moves both directions so, it is referred as bidiectional. Bi means two.
36. The answer is a. The leading strand is synthesized continoulsy in the 5'>3' direction white the lagging strand is synthesized discontinoulsy in 5'>3'
37. The answer is b. The origin of replication.
The ori site has two different repeat sites one with 13bp and another 9 bp. The ori site has 3 units of 13bp and four untis of 9 bp site. Which is mostly composed with A and T basepairs. Here the replication occurs.
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