Sometimes mutations involve the deletion of large regions of genetic information

Question

Sometimes mutations involve the deletion of large regions of genetic information. Other mutations affect gene expression by altering the DNA sequence of regulatory elements like promoter regions. Further analysis reveals that your patient appears to have a mutation that affects mRNA splicing (removal of introns and splicing together of various exons), which occurs approximately mutation reduces the level of mature mRNA in his cells. This is why the level of the affected gene shows a lower expression level than controls in your patient, Lee. 5. % of the time in this condition. This

Explanation / Answer

Mutation is process that involves deletion of large regions of genetic information.other mutations affect gene expression by altering the DNA sequence of regulatory elements like promoter regions.further analysis reveals that your patients appears to have a mutation that affects mRNA splicing which occurs approximately 50% of the time in this condition. This mutation reduces the level of mature mRNA in his cells.this is why the level of affected gene shows lower expression level than controls in your patients.

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