2. In a prospective cohort study, persons who wear contact lenses are compared t

Question

2. In a prospective cohort study, persons who wear contact lenses are compared to persons who only wear glasses regarding the incidence of eye infections. Each person is followed for a one year period with no loss to follow-up. As part of your investigation, you need to assess whether age is a potential confounder or effect modifier. The results are shown below for persons above or below 40 years of age.

a. What is the most appropriate measure of association for this study?

b. Using this measure of association, does age modify the association between contact lens use and eye infection? Why or why not? (If age is an effect modifier, then stop after answering part b. If age is not an effect modifier, then continue with parts c and d.)

c. If age is not an effect modifier, does age confound the association between contact lens use and eye infection? Why or why not?

d. If age is not an effect modifier, show how age either meets or does not meet each of the criteria for confounding.

Explanation / Answer

A)

The appropriate measure for above prospective cohort study, here it measures the strength and weakness of the study by observing risk factors of in the study.

B)

The age effects the modifier because above 40 years age they may have risk of eye infection. So the age is effecting the modifier.

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