1.Which of these factors might impair the absorption of an oral medication? Rena
ID: 243114 • Letter: 1
Question
1.Which of these factors might impair the absorption of an oral medication?
Renal Insufficience
Hepatic Insufficiency
The presence of food in the stomach
High Serum Albumin
QUESTION 2
2. A client reports that he has been swallowing his nitroglycerin instead of leaving it
under is tongue. Teaching is needed. What can happen if sublingual medications
are swallowed?
a. Gastric acid may inactivate the medication.
b. The medication effects will be increased due to the first pass effect.
The medication effects will simply be delayed.
An esophageal burn may occur.
3.The nurse is wondering if advocacy for a change to oral medication instead of an IV
route of administration is appropriate. What rationale for advocacy would be
appropriate?
Oral medications are more completely absorbed than IV medications.
A serious infection or injury may start at the site of the IV insertion.
IV medications are more vulnerable to the first pass effect than oral
medications.
IV medications should only be given to clients who cannot swallow.
4.If phenobarbital has a four day half-life and a client accidently took 200mg of the
drug on Tuesday morning and no intervention occurred, how much medication will
remain in the bloodstream of that client on Thursday morning?
100mg
150mg
50mg
75mg
5. A malnourished elderly client has a low serum albumin level. What is the implication
of this finding? (Select only ONE answer)
Low serum albumin levels will lead to receptor disintegration so more
medication will be needed.
Protein insufficiency can lead to loss of metabolizing enzymes and
consequential decrease in drug levels.
Less protein binding will occur and more medication will be free to bind with
target receptors. This may cause excessive effects.
Blood brain crossover will be impaired. Albumin is a lipid. More medication will
be needed.
6. A laboring mother wants to know why pain medication is not advisable. What
rationales could the nurse offer to explain this? (Select all that apply.)
The blood brain barrier of a fetus is not fully developed so the fetus is at risk for
sedation.
The liver of a fetus is not well developed so the effects of sedation could linger
in the fetus.
Epidural anesthesia offers an alternative that will not harm the fetus.
The fetus will not be able to eliminate the medication until it has its first stool.
7. A client who takes Theo-24 (theophylline) for asthma is experiencing theophylline
toxicity. Which of these may be a contributing factor? (Select all that apply.)
Chewing the capsule
Cirrhosis with gallstones
First pass effect
Forgetfulness causing double dosing
8. Which comment about over-the-counter (OTC) medications indicates the need for
further teaching?
People who take other medications should consult their provider before taking
OTCs.
While safe for the general public, they may be unsafe for people with renal or
hepatic disease.
c.They tend to have a high therapeutic index.
They are generally safe to take while pregnant.
9.Which of these is not an essential part of a medication order?
The dose of the medication must be indicated.
Both the trade and generic names must be cited together.
The route of the medication must be indicated.
The client's name must appear on the order sheet.
a.
Renal Insufficience
b.Hepatic Insufficiency
c.The presence of food in the stomach
dHigh Serum Albumin
Explanation / Answer
1) Hepatic insufficiency
Mist of the drug which is administered are absorbed by liver as it acts as first pass for most of the drug
2)The medication effect will be simply delayed
Because Nitroglycerin acts very fast when given sublingually through the lining of mouth I'm 1 to 5 minutes
Hence swallowing it may delay the action
3)A serious infection or injury might start at the site of insertion
A medicine to patient is administered depending upon the need and necessity of absorption and acting in patient body to relieve problem.
4)150 mg
Half life of a drug means the effect of the medicine comes down to half dosage in body in particular days as per the type of medicine
Here Half life is 4 days,that is on fourth day the dose will be half in the body ( 200= 100mg on 4 th day,)
But the patient is on 3 rd day so it is 150mg
7) forgetfulness causing double dosing
This may lead to toxicity
8)they are safe to take during pregnancy
No medicine to be taken without physicians prescription
9)Both the generic and trade name s must be cited today
Because this may lead to confusion
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