1. Consider two blood polymorphisms in addition to the ABO blood group. The domi

Question

1. Consider two blood polymorphisms in addition to the ABO blood group. The dominant Rh allele
confers the Rh+(rhesus positive) phenotype, whereas the recessive rh allele confers the Rh-
(rhesus negative) phenotype. Two codominant alleles, LM and LN determine the M, N, and MN blood groups.

Two men took a paternity case to court, each claiming three children to be his own. The blood groups of the
men, children, and the mother of the children were as follows:

Person Blood group

Husband A M Rh+

Wifes lover AB MN Rh-

Wife B MN Rh+

Child 1 O M Rh-

Child 2 B N Rh-

Child 3 B MN Rh+

From this evidence, can the paternity of the children be established (assuming no additional lovers)? List
the likely male parent for each child and give your reasons (briefly). If paternity cannot be established in
one or more cases, again give your reasons.

Explanation / Answer

==================================
Child 2 B N Rh- --------------

Child 3 B MN Rh+ --------------------

Wife’s lover ---------AB----------I^A I^B         X Wife’s---------I^O I^B

0 group-----OFFSPRONG -------group----genotype----I^o I^o         -NOT POSSIBLE

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