A 38 year old man had a history of soft tissue bleeding after minor trauma. He r

Question

A 38 year old man had a history of soft tissue bleeding after minor trauma. He required 4 units of blood following a hemorrhoidectomy.

Bleeding time:                        4 min

Platelet Count:                       300,000/cumm

PT:                                          12 sec

APPT:                                      55 sec

TCT:                                        10 sec

Fibrinogen:                            275 mg%

1. What is the most probable diagnosis?

2. What additional tests should be performed to confirm the diagnosis?

Explanation / Answer

1.the most probable diagnosis is hemophilia.in hemophilic conditions all blood values like bleeding time, platelet count,PT,TCT etc will be normal except APTT.it may prolong.

2.clotting factor test called factor assay can do to measure factor VIII and IX.

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