Female mammals, including women, sometimes develop benign tumors called \"ovaria
ID: 24174 • Letter: F
Question
Female mammals, including women, sometimes develop benign tumors called "ovarian teratomas" or "dermoid cysts" in their ovaries. Such a tumor begins when a primary oocyte escapes from its prophase I arrest and finished meiosis I within the ovary. (Normally meiosis I does not finish until the primary oocyte is expelled from the ovary upon ovulation.) The secondary oocyte then develops as if it were an embryo, and it implants and develops within the follicle. Development is disorganized, however, and results in a tumor. If a dermoid cyst forms in a woman whose genotype is Aa, what are the possible genoytpes of the cyst?
Explanation / Answer
CF has many possible genotypes. There are currently about 100 markers that are most likely to result in the disease, but there are actually even more than that. I used to work for a company that did testing for this disease, and any two of the 100 markers would result in CF. There is a "most common" genotype, but there are many other combinations possible.
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