6. Of the NOACs, which have been associated with a higher risk of gastrointestin

ID: 240622 • Letter: 6

Question

6. Of the NOACs, which have been associated with a higher risk of gastrointestinal bleeding?

a. Edoxaban and rivaroxaban

b. Apixaban and dabigatran

c. Dabigatran and rivaroxaban

d. Apixaban and edoxaban

7. Compared to warfarin, which finding have all NOACs not shown a lower risk for?

a. Major bleeding

b. Gastrointestinal bleeding

c. Intracranial hemorrhage

d. Recurrent VTE

8. What is the appropriate dose of idarucizumab for the reversal of dabigatran?

a. 2.5 g IV bolus ×1

b. 5 g IV bolus ×1

c. 2.5 g IV bolus ×2, no more than 15 minutes apart

d. 5 g IV bolus ×1, repeated only if needed within 15 minutes

9. In the absence of bleeding, at what level do the 2016 VTE guidelines recommend against the use of vitamin K for INR reversal?

a. 4.5

b. 7

c. 10

d. 12

6)c) Dabigatran and riveroxaban

Higher doses of these drugs increase the chances of GI bleeding.

7)a)GI bleeding

This still remains the common side effects of both warfarin and NOAC.

8)c) 2.5g IV bolous×2,no more than 15 mins.

9)a)4.5 For values equal to or less than 4.5 VIT K should be withheld

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