Use the below scenario to answer questions 23-30 You follow a group of 3,000 wom
ID: 239697 • Letter: U
Question
Use the below scenario to answer questions 23-30 You follow a group of 3,000 women for 10 years (from 1990 to 2000) with liver cirhosis (LC) as your outcome. In 1990 nobody had LC. Of those who drank alcohol daily (n-1,200) in 1990, 160 were diagnosed with LC during the 10 year period. Of the abstainers in 1990, 80 had LC diagnosed during the 10 year period. Construct your table from the above data and answer questions 23-30. Remember, your total number of women in your table must be 3,000. Nobody died during 1990-2000. Total Total ,000 23. Please complete the table above with the numbers AND the proper headings for columns and rows 24. What is your relative risk for the above data? 25. Interpret (articulate) your findings from item #24. Assume that the RR is statistically significant.Explanation / Answer
1990-2000
Liver Cirrhosis
No Liver Cirrhosis
Total
Alcoholics
160 (A)
1040 (B)
1200 (A+B)
Abstainers(Non alcoholics)
80 (C)
1720 (D)
1800 (C+D)
Total
240 (A+C)
2760 (B+D)
3000
24.RELATIVE RISK:
Relative risk or risk ratio (RR) is the ratio of the probability of an event occurring (for example, developing a disease, being injured) in an exposed group to the probability of the event occurring in a comparison, non-exposed group.
Here, the exposed group is the alcoholic women and the non exposed group is the abstinent women. The event/disease is Liver Cirrhosis here.
Formula to calculate Relative risk :
Relative risk = A/(A+B)
C/(C+D)
= 160/1200
80/1800
= 0.1333
0.0444
Relative risk =3.02
25.Interpretation of the finding
Since the RR in the given question is 3.02 (that is, more than 1), the alcoholic women are having more risk than the abstinent women to develop liver cirrhosis.
Alcoholic liver disease is a major source of alcohol related morbidity and mortality. Heavy drinkers and alcoholics may progress from fatty liver to alcoholic hepatitis to cirrhosis. The likelihood of developing Liver Cirrhosis is, to a large extent, a function of both the duration and amount of heavy drinking, and the per capita consumption of alcohol within populations has been shown to be a strong determinant of cirrhosis morbidity rates.
The recommendation for the study is educating women on the ill effects of alcoholism and preventing the occurances of Liver Cirrhosis.
1990-2000
Liver Cirrhosis
No Liver Cirrhosis
Total
Alcoholics
160 (A)
1040 (B)
1200 (A+B)
Abstainers(Non alcoholics)
80 (C)
1720 (D)
1800 (C+D)
Total
240 (A+C)
2760 (B+D)
3000
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