Lakerdal is a drug used to treat parasitic infections. Its properties are. Log\"

Question

Lakerdal is a drug used to treat parasitic infections. Its properties are. Log" MWt 319, pKa . 6. Below ere the approximate pH of gifferent compartments within a parositep-ven Mitochondria 8 1. In which compartment within the cell will you expect find the drug mostly in the unionized form a b. Golgi body ytosol d. mitochondria none of these E cytosel d. mitochondria enone of these 2. A pro-drug is a A drug given to promote growth b. A drug given in its active form c. A drug given to prevent metabolism of another drug A drug given in its inactive form, requiring metabolism 3. X is a pro-drug that requires CYP2C19 for activity: Y is drug that induces CYP2C19. What will happen to the therapeutic effect of drug X if used concurrently with drug y Does not change b. Decrease c. Increase d. information inadequate to answer question in the treatment of acute coronary syndrome is A. TRUE 4. The binding of Aspirin to Cyclooxygenase FALSE reversible in biological systems The cytochrome P-450 enzyme that is responsible for the oxidation of the majority of foreign chemicals that enter the body is 5 d, CYP2D6 CYP3A4 a. CYP1A2 b. CYP286 c. CYP2C9 Figure (right), Quantal dose response curve for drug 6. In the figure, which of the doses is likely the LDso Dose 7· The Therapeutic Index (TI) is used to: Determine how effective a therapeutic drug is b. Compare the therapeutically effective dose to the toxic dose of a drug c. Calculate the lethal dose level for different pharmaceuticals d. Compare the lethal dose to the therapeutically effective dose of a drug 8. Metabolism, or biotransformation, of a xenobiotic may result in a reduced toxicity of the xenobiotic increase toxicity of the xenobiotic a metabolite of lower logP than the original xenobiotic prolong the effect of the xenobiotic all of the above c. d. 9. cimetidine is a Pan-CYP inducer A. True B. False

Explanation / Answer

1.c.cytosol

2.d.a drug given in its inactive form,requiring metabolism

3.b.increases

4.false

5.c.cyp2c9

6.c

7.d,compare the lethal dose to the therapeutically effective dose of a drug.

8.d.prolong the effect of the xenobiotic.

9.false

Related Questions

Navigate

• Browse (All)
• Browse L
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.