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In mice, black coat color (B) is dominant over brown (b), and a solid pattern (S

ID: 23334 • Letter: I

Question

In mice, black coat color (B) is dominant over brown (b), and a solid pattern (S) is dominant over white spotted (s). Color and spotting are controlled by genes that assort independently. A homozygous black, spotted mouse is crossed with a homozygous brown, solid mouse. All the F1 generation are black and solid. A testcross is then carried out on the F1 mice.

Give the genotypes of the parents and the F1 mice, then give the genotypes and phenotypes, along with their expected ratios, of the progeny expected from the testcross.

Explanation / Answer

In mice, black coat color (B) is dominant over brown (b), and a solid pattern (S) is dominant over white spotted (s). Color and spotting are controlled by genes that assort independently. A homozygous black, spotted mouse is crossed with a homozygous brown, solid mouse. All the F1 generation are black and solid. A testcross is then carried out on the F1 mice.

Give the genotypes of the parents and the F1 mice, then give the genotypes and phenotypes, along with their expected ratios, of the progeny expected from the testcross.

In mice, black coat color (B) is dominant over brown (b),

and a solid pattern (S) is dominant over white spotted (s).

homozygous black, spotted mouse--------BBSS

homozygous brown, solid mouse.-----genotype---------bbss

                                                        BBSS X bbss-----------parents

All the F1 generation are black and solid. genotype---------BbSs

TEST CROSS

F1 genotype—BbSs             X   bbss

gametes

BS

bS

Bs   

bs   

bs

BS bs

bS bs

Bs   bs

bs bs

bs

BS bs

bS bs

Bs   bs

bs   bs

bs

BS bs

bS bs

Bs bs

bs   bs

bs

BS bs

bS bs

Bs   bs

bs   bs

Test cross ratio =1:1:1:1

genotype

phenotype

BS bs

black, spotted mouse

4/16

bS bs

brown, spotted mouse

4/16

Bs   bs

black, spotted mouse

4/16

bs bs

brown, solid mouse.-----

4/16

gametes

BS

bS

Bs   

bs   

bs

BS bs

bS bs

Bs   bs

bs bs

bs

BS bs

bS bs

Bs   bs

bs   bs

bs

BS bs

bS bs

Bs bs

bs   bs

bs

BS bs

bS bs

Bs   bs

bs   bs

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