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The hemoglobin produced in the body of an infant A)has a higher Kd for BPG than

ID: 2281 • Letter: T

Question

The hemoglobin produced in the body of an infant A)has a higher Kd for BPG than would be excepted for adulthemoglobin B) is comprised if two beta and two gamma subunits C)contains gamma subunits that place negatively charged sidechains in the BPG binding site The hemoglobin produced in the body of an infant A)has a higher Kd for BPG than would be excepted for adulthemoglobin B) is comprised if two beta and two gamma subunits C)contains gamma subunits that place negatively charged sidechains in the BPG binding site

Explanation / Answer

The subunit has less positive charges than the adulthemoglobin b subunit. This means that 2,3-bisphosphoglycerate(2,3-BPG) is less electrostaticly bound to fetal hemoglobin ascompared to adult hemoglobin.
Fetal hemoglobin is composed of two alpha and two gammasubunits So then the answer must be C) contains gamma subunits thatplace negatively charge side chains in the BPG binding site