In what order do you place the following events? .... (some of them seem counter

ID: 227523 • Letter: I

Question

In what order do you place the following events? .... (some of them seem counter active)

1) G protein (,,:GDP) binds to activated receptor forming a receptor-G protein complex

2) GTP- binds to the effector Stimulating cAMP production

3) Receptor causes nucleotide exchange (,,:GDP) become (,,:GTP)

4) The G protein hydrolyzes GTP, and the G protein complex is formed (,,:GDP)

5) The secondary messenger binds to a kinase activating a phosphorylation cascade

6) Binding of a Ligand to a G-protein coupled receptor

7) GTP- dissociates from complex and diffuses away

8) Arrestin binds the Activated receptor and it is brought into the cell for recycling.

Binding of a Ligand to a G-protein coupled receptor

G protein (,,:GDP) binds to activated receptor forming a receptor-G protein complex

Receptor causes nucleotide exchange (,,:GDP) become (,,:GTP)

GTP- dissociates from complex and diffuses away

GTP- binds to the effector Stimulating cAMP production

The secondary messenger binds to a kinase activating a phosphorylation cascade

Arrestin binds the Activated receptor and it is brought into the cell for recycling.

The G protein hydrolyzes GTP, and the G protein complex is formed (,,:GDP)

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