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The existence of 64 different codon triplets and 20 different amino acids is rec

ID: 227216 • Letter: T

Question

The existence of 64 different codon triplets and 20 different amino acids is reconciled in the cell by:

failure to use most of the available triplets as mRNA codons.

wobble in which the 3' nucleotide of the anticodon can pair loosely with the codon.

wobble in which the 5' nucleotide of the anticodon can pair loosely with the codon.

an aminoacyl-tRNA synthetase that recognizes over 60 different tRNAs.

the cell has not figured this one out yet.

A.

failure to use most of the available triplets as mRNA codons.

B.

wobble in which the 3' nucleotide of the anticodon can pair loosely with the codon.

C.

wobble in which the 5' nucleotide of the anticodon can pair loosely with the codon.

D.

an aminoacyl-tRNA synthetase that recognizes over 60 different tRNAs.

E.

the cell has not figured this one out yet.

Explanation / Answer

Ans C wobble in which the 5' end of nucleotide of the anticodon can pair loosely with the codon.

Wobble hypothesis was given by Francis crick according to which 3rd base of anticodon loop may have a base pair ionosine that helps tRNA bind with more than 1 codon thus preventing the need of as many as 61 tRNA molecules.

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