You have been assigned to care for Mr. P, a 44-year-old patient recently diagnos

Question

You have been assigned to care for Mr. P, a 44-year-old patient recently diagnosed with peptic ulcer disease. He has a 15-year history of smoking cigarettes and takes ibuprofen [Motrin] regularly for an old football injury to his knee. He has been prescribed cimetidine. You are teaching him how to manage his peptic ulcer disease and other conditions.

Discuss the relationship of mucosal defenses and aggressive factors to health and peptic ulcer disease. (Look at Figure 78-1 on p. 948). What factors protect against or lead to ulcer formation. Remember that the protective factors are the basis for pharmacologic intervention!

Mr. P says, “When I take an antacid, like Rolaids, I feel better. Why can’t I take antacids anymore? That’s what the doctor told me.” What is your best response?

He states, “I have a headache, and my knee hurts. I need an aspirin or a Motrin.” What is your best response?

Explanation / Answer

Physical activity provides a non pharmacologic method of reducing the incidence of ulcers among men. Ulcer is caused by lifestyle factors which causes digestive tract unable to protect itself from the acid content of the stomach. The use of NSAIDs can also cause peptic ulcers.

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