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Hooper hypothesized that HIV-1 first entered humans in which decade? 1920s 1930s

ID: 226276 • Letter: H

Question

Hooper hypothesized that HIV-1 first entered humans in which decade? 1920s 1930s 1940s 1950s 1 960s In Exercise 1 (Molecular Evolution), how would you describe the change in variation of the virus population after 1000 generations? There is more variation after 1000 generations. There is less variation after 1000 generations Amount of variation is about the same after 1000 generations. In Exercise 3 (Diverging Lineages), you generated a best fit line for differences vs. generation. What was the slope of that line? Positive Negative Flat Unknown, because the line could not be generated.

Explanation / Answer

Please find the answers below:

Part 1: Choice 2 (According to demographic data and clinical observations, it has been suggested by the Hooper's hypothesis that the HIV virus had been first introduced in humans and caused infection between 1915-1941 and most probably in the 1930s. This data has been published in prestigious research publication journal as well)

Part 2: Choice 1 (The number of variations are highly likely to increase with time because the viral genome does not carry a repair mechanism of their own and rely upon host genome for it. This causes accumulation of various mutations in the viruses and hence, the rate of variation in viral genome increases with time)

Part 3: Choice 2 (Since viral genome undergoes variations with respect to their generation number, the line of bet fit will be progressively increasing with the number of viral generations. This will make the slope of this best fit line negative in nature suggesting that there is negative regulation between the mutual differences and number of generations between viruses.)