This problem refers to the MN and ABO loci mentioned in class. It also refers to

Question

This problem refers to the MN and ABO loci mentioned in class. It also refers to the Rh locus, which is responsible for the positive/negative part of the blood type. The Rh+ allele is dominant to the Rh- allele at this locus. Select all couples who could be the parents of a child with phenotype MN, B- based on the phenotypes at these three loci. If none of these couples could be the parents of this child, select "None of These".

Select one or more:

a. Mother Type MN, B+ and Father Type N, O+

b. Mother Type MN, AB- and Father Type M, O-

c. Mother Type MN, O+ and Father Type MN, A-

d. Mother Type M, A+ and Father Type N, B-

e. None of These

Explanation / Answer

Answer: Couples who could be the parents of a child with phenotype MN, B-

b. Mother Type MN, AB- and Father Type M, O-

d. Mother Type M, A+ and Father Type N, B-

Explanation: Option:a both parents have Rh+ , so they can not have a child with B- group

Option: c, parents have A- and O+ groups so they can not have a child with B group(BB or BO are the genotypes a B blood group child should have) these genotypes can not be formed from A and O parents

Option b and d couples might have child with  phenotype MN, B-, since the gene combinations are present in the couples.

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