1. Which of the following is the cell type most directly relevant to battling th

Question

                    1. Which of the following is the cell type most directly relevant to battling the pathogens the bullet likely                 

                    carried into the brain of Rep. Gabrielle Giffords?                 

                    A. Schwann cells                 

                    B. microglia                 

                    C. oligodendrocytes                 

                    D. astrocytes                 

                    E. arachnoid villi                 

                    2. Which of the following is a cell type important for re-myelinating axons in damaged portions of the                 

                    recovering brain of Rep. Gabrielle Giffords?                 

                    A. Schwann cells                 

                    B. microglia                 

                    C. oligodendrocytes                 

                    D. astrocytes                 

                    E. arachnoid villi                 

                    3. Which of the following is the cell type interacting with endothelial cells via endfeet in the recovering brain                 

                    of Rep. Gabrielle Giffords?                 

                    A. Schwann cells                 

                    B. microglia                 

                    C. oligodendrocytes                 

                    D. astrocytes                 

                    E. arachnoid villi                 

                    4. Rep. Gabrielle Giffords had to remain in the intensive care unit for longer than originally planned                 

                    because of excessive intracranial pressure. Which of the following is most relevant to the uptake of the fluid                 

                    responsible for causing this pressure?                 

                    A. carotid artery                 

                    B. choroid plexus                 

                    C. oligodendrocytes                 

                    D. astrocytes                 

                    E. arachnoid villi                 

                    5. Which of the following correctly describes how myelination alters the passive properties of the neuronal                 

                    membrane?                 

                    A. causes faster decay of depolarization by reducing resistance                 

                    B. increases resistance, reduces capacitance                 

                    C. regenerates the action potential after skipping a large stretch of axon                 

                    D. decreases flux through Na+ channels, thereby speeds up action potential                 

                    E. none of the above are completely correct                 

                    MCDB 4777/5777 2/2/11 EXAM I Page 2                 

                    6. Which factors contribute to the squid axon

Explanation / Answer

1 C. oligodendrocytes

2 C. oligodendrocytes

3 A. Schwann cells

4 B. choroid plexus

5)E. none of the above are completely correct

6) D. inactivation domain of calcium gated potassium channel; flux through inward rectifier potassium

7)D. the potassium channels only allow ions to flow one way

8)A. ligand-gated ion channels

9)b. the sodium channel gene family likely evolved so that multiple different sodium channels can be

10 e. testing whether changing the concentration of an ion influences membrane voltage

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