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in furtherundentanding the eraltransduction pathway that controls the production

ID: 225841 • Letter: I

Question


in furtherundentanding the eraltransduction pathway that controls the production of pigu. You are prolein important for regulating cell size. phosphorylates the szE transcription szE only intrracts with the nuclear transport receplor when phosphorylated. SZEisa gene activator for the Ped gene. This pathway is diagrammed in FigaReQ16s0 Fizure Q16.50 Normal cells grown undet standard conditions (without ligand ae l4 pun in diameter willle normal cells exposed to TRK liguild are 10,5 um in diameter Givenths situation, which of the sillowing condilions do you predict will more likely lead to smaller cells A! addition TRk ligand and a duas that sumulates the kirlase activity of Ras additious of TRK liland and a dug that inhibt the actave of the plasplulase that acts on szE addision TRK lyand and a drug that inhibits bindina to Dea What follon, A MAP kinse is mentant fai Ilvesrdurylalay MAP kinase kinawc

Explanation / Answer

C) Addition of TRK ligand and a drug that stimulates the degradation of pig 1 gene

The TRK ligand or the TRK gene is activating the Ras pathway , thus , the first option where stimulation of GTPase is given is not required as it will be anyway stimulated with the activation of TRK. If the phosphates is inhibited then it will not bind to nuclear transport receptor. If pig 1 doesn't bind to DNA, then the DNA will not be shortened , thus the answer will be C.

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