Among the differences between fatty acid synthesis and fatty acid oxidation is t

Question

Among the differences between fatty acid synthesis and fatty acid oxidation is the fact that

A. synthesis occurs in the mitochondria and oxidation in cytosol.

B. synthesis uses NADH and oxidation uses FAD.

C. synthesis is accelerated and oxidation depressed in diabetes.

D. malonyl-CoA is an intermediate in oxidation, but not in synthesis.

E. the acyl groups form different thioesters in synthesis and oxidation.

A. synthesis occurs in the mitochondria and oxidation in cytosol.

B. synthesis uses NADH and oxidation uses FAD.

C. synthesis is accelerated and oxidation depressed in diabetes.

D. malonyl-CoA is an intermediate in oxidation, but not in synthesis.

E. the acyl groups form different thioesters in synthesis and oxidation.

Explanation / Answer

A. synthesis occurs in the mitochondria and oxidation in cytosol. True ( The fatty acid synthesis occurs when pancreas detects high levels of blood glucose, which indicates body has sufficient energy intake therefore, excessive carbohydrates gets converted to fats.) and when there is less of the intake and body needs to use it's reserve then there is excess of fatty acid oxidation which take place in mitochondria)

B. synthesis uses NADH and oxidation uses FAD. true

C. synthesis is accelerated and oxidation depressed in diabetes. False ( As glucose cannot move inside the cell theefore, it's concentration remains low in the cytosol.

D. malonyl-CoA is an intermediate in oxidation, but not in synthesis. False (Malonyl-CoA is used in fatty acid synthesis with the help of enzyme malonyl coenzyme A)

E. the acyl groups form different thioesters in synthesis and oxidation. False

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