(12). Indicate if the following statements are true or false. If false, explain
ID: 220247 • Letter: #
Question
(12). Indicate if the following statements are true or false. If false, explain why it is false. (1 point each) (a). Both G-coupled receptors and receptor tyrosine kinases may activate phospholipase C. (b). Some signaling molecules, like steroid hormones, can diffuse through the cell membrane and can bind directly to DNA to activate gene expression (c). Ras becomes activated when a receptor tyrosine kinase phosphorylates the bound GDP bound to RAS to create GTP (d). Adenylyl cyclase is a transmembrane protein that is synthesized in the ER. (e). A mutation in Ras, leading to its inability to exchange GDP for GTP, is associated with a large number of human cancers.Explanation / Answer
a. True. Both activates.
b. True. Hormones diffuses and alters the gene expression.
c. True. Binding of the hormones causes dimerization and autophosphorylation of tyrosine residues. Which causes conformational changes that permits release of GDP and facilitate binding of GTP, forming active Ras.
d. True. As it is transmembrane protein it will synthesized in rough endoplasmic reticulum.
e. True. Ras basically controls the amount of the growth at the particular time due to cancer mutation, Ras not able to control the growth.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.