Which of the statements below IS NOT CORRECT about DNA repair mechanisms? A) DBS
ID: 218841 • Letter: W
Question
Which of the statements below IS NOT CORRECT about DNA repair mechanisms? A) DBS (double stranded break repair) may result in loss and or alteration (mutation) of original DNA information. B) specific DNA repair mechanisms such as MMR (mismatch repair) and BER (base excision repair) differ in the way they recognize the damaged region, however both employ a nuclease to remove faulty DNA sequences, a DNA polymerase to fill the gap and a ligase to join DNA strands. C) NMR (mismatch repair) and BER (base excision repair) use a DNA homology matching system (MSH) to identify damaged DNA. D) a generic DNA repair mechanism involves a mismatch (or damage) recognition complex, a nuclease that removes the surrounding DNA, a DNA polymerase to reconstruct the damaged region and a DNA ligase to join the newly synthesized DNA strand with the existing.
Explanation / Answer
The incorrect statement seems to be C) NMR (mismatch repair) and BER (base excision repair) use a DNA homology matching system (MSH) to identify damaged DNA.
As it is the DBS that uses homology to repair DNA.
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