Question 1 In chromatin, DNA is bound to proteins which regulate its packaging a

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Question 1 In chromatin, DNA is bound to proteins which regulate its packaging and also access to the sequence/gene A. This is a structure found predominantly in the nucleolus B. Histone proteins form the core of the nucleosome around which the DNA is wound. c Mistone proteins can be chemically mdifled by enzymes and these modifications afflect how tighty . C C or "loosely" the DNA is associated with the core D.Two of the above E All of the above. Question 2 You conducted a modifier screen for mutants that affect the PEV eye color phenotype and identfed a e(var) mutant. This means that for this mutant " A there are more white eye cells n the eyes of the mutant fies as compared to the parental PEV A. there are mutant flies B the spread of heterochromatin is decreased gene has been inverted and is now closer to the euchromatin in the locus for the the telomeric region of the chromosome D. Two of the above E All of the above Question 3 Bacteria with mutations in the lac operon and related genes have been created in your analysis of one of the mutants, you note that the operon is constantly transcribed and is increased in the absence of glucose. You conclude that the mutation is likely to be in A. the gene that codes for CAP B. the operator (ilaco) C the repressor (laci) D. Two of the above EAII of the above C Question 4 Which of the following is involved in the sensing of tryptophan levels in the cel? C A. Attenuator sequence Region 1 (" B Attenuator sequence Region 2 C C Attenuator sequence Region 3 D.Attenuator sequence Region 4 The two trp codons in the leader region

Explanation / Answer

1) D- all of the above

2) C-the locus of the white gene has been inverted and is now closer to the euchromatin in the telomeric region of the chromosome.

3) E-all of the above

4) A-attenuation sequence region one

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