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10. Five nucleotide positions across a 1 Mb region have been found to vary in a

ID: 21814 • Letter: 1

Question

10. Five nucleotide positions across a 1 Mb region have been found to vary in a human population of South Africa showing a clear pattern of linkage disequilibrium. Six chromosomes of such population are shown below. a) Indicate how many different haplotypes (common and rare) do you observe across the sequences compared. b) Propose Tag SNPs that can summarize the nucleotide diversity in the genomic region under study.
Chromosome 1 A G G T C
Chromosome 2 C A T C G
Chromosome 3 A G G T C
Chromosome 4 A G G T C
Chromosome 5 A G G T C
Chromosome 6 C A T C G

Explanation / Answer

Chromosome 3 A G G T C

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