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Mukai and Burdick set up population cages of fruit flies in which one allele was

ID: 21796 • Letter: M

Question

Mukai and Burdick set up population cages of fruit flies in which one
allele was lethal as a homozygote and the other had a fitness of 0.74 as
a homozygote. Populations initiated at frequencies of 0.98 and 0.50
for the viable allele converged to an equilibrium frequency of roughly
0.8. The best explanation for this convergence is
a. homozygote lethality. b. heterozygote lethality.
c. heterozygous superiority.
d . balanced nondisjunction. e. heterozygote sterility.


8. The decline in frequency of a lethal or severely deleterious allele
which is recessive is fairly rapid when this allele is common, but it
is very, very slow when the deleterious allele becomes rare. This
accounts for the large number of rare, deleterious alleles. The slow
decline for rare, recessive alleles is attributable to the fact that
a.. recessive homozygote frequency is q2. b. A2A2 is dominant.
c. recessive alleles are always bad. d. selection is weak on lethals.

The Hardy-Weinberg Equilibrium Law assumes (a) an infinite size
population, (b) no mutation or migration, (c) no selection and (d)
random mating. Under these conditions even populations not in
equilibrium will a. attain equilibrium in a generation and stay in equilibrium forever.
b. achieve mutation-selection equilibrium in one generation. c.drift from one allele
frequency to another. d. show remarkable increases in genetic variability.
e. attain equilibrium in n-q generations


5. If the frequency of the R allele is p at generation zero, and the frequency of the R1 allele is q, we may predict the progeny frequencies for the next generation when the Hardy-Weinberg assumptions apply as ( p+ q)2. The frequency of R amongst the progeny is p

Explanation / Answer

c. heterozygous superiority a.. recessive homozygote frequency is q2. b. achieve mutation-selection equilibrium in one generation c. p’ = 2pq d

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