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s. You and your research team are working on a new mammal species (2n -omatic 74

ID: 217362 • Letter: S

Question

s. You and your research team are working on a new mammal species (2n -omatic 74) that appears to be susceptible to type one diabetes. One of your students has established a soma the following results. In which of the 74 chromosomes is the gene on? Explain. line # (5 pts) the gene on? Explain sell ybrid panel with Chromosomes Assay* 1 7, 10, 15, 29, 41, 55, 68 2 4, 8, 16, 31,44, 56, 70 3 9, 12, 18, 52, 54, 61, 73 + 4 1,8, 13, 22, 33, 45, 59 5 2, 11, 14, 18, 23, 49, 62 6 5,12, 15, 24, 35, 47, 63 - 7 3, 17, 21, 32, 43, 58, 72 7, 21, 25, 36, 53, 64 9 1,3, 9, 28, 37, 48, 65 10 4,6, 12, 18, 20, 40, 67 Positive sign (+)-insulin is expressed Negative sign ()-insulin is absent

Explanation / Answer

The gene is on in chromosome number 18.

We compare the insulin expressed( + sign) line. While comparing all the 3 lines we get only chromosome 18 as a common which suggest that this 18 is responsible for expressing insulin.

chromose 18 is the one which is the gene is on is confirmed by also looking for chromosome 18 in all the negative (- ) lines. There is no chromosome 18 in other cell line.