A study of congenital anomalies (birth defects) and prenatal exposure to antihis
ID: 216581 • Letter: A
Question
A study of congenital anomalies (birth defects) and prenatal exposure to antihistamines compared 250 infants born with congenital heart defects with 250 healthy infants who were born in the same months in the same hospitals. Among the children with heart defects 50.0% of their mothers used antihistamines during pregnancy, while among the healthy infants, only 25.0% of the mothers used antihistamines during pregnancy Answer the following in the space below A. What type of study is this? B. Calculate the appropriate measure of association (Show your work for partial credit. If you want to show your 2x2 table, you can use the table function to enter your table) C) Is prenatal exposure to histamines associated wtih congenital heart defects? Explain your answer Bonus (+2 points) D) Can incidence be calculated from this study? If so, what is the incidence of congenital heart defects?Explanation / Answer
Drug exposure
250. 250
Case control study: as it started from disease to cause
Association: strength of association is equal to odds ratio ad/bc
=a*d/b*c=2.96
Yes prenatal exposure to histamines associated with. Congenital heart defects are of 80% unknown ethnology they might be drug exposure and radiation and maternal life style factors like smoking Here in this case the association is more indicating that they both are linked
Incidence of congenital heart defects globally is 10-12 per 1000 population
Drug exposure
Heart defects No defects Yes 125(a) 63(b) No 125(c) 187(d)Related Questions
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