10)Consider the genetics of the ABO blood groups. A man of blood gropu B is bein
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Question
10)Consider the genetics of the ABO blood groups. A man of blood gropu B is being sued by a woman of blood group A for paternity. The woman's child is blood group O. (a) is this man the father of this child? Explain. (b) If this man actually is the father of this child, specify the genotypes of both parents. (c) If it was impossible for this group B man to be the father of a type O child, regardless of the mother's genotype, specify his genotype. (d) If a man was blood group AB, could he be the father of a group O child?Explanation / Answer
The alleles for blood group in humans are Ia, Ib and i.
For blood group A ,we have IaIa and Iai
For B , we have IbIb and Ibi
For AB -IaIb
For O- ii
(a) As the man has blood group B then he will have alleles for blood group as
1. Ib and i or
Ib and Ib
And mother can have alleles as
1. Ia and Ia
2. Ia and i
So the possible combinations are
IaIb-blood group AB
Iai-blood group A
Ibi-blood group B
ii-blood group O
So the conclusion is that the man can be father of child if he has genotype as (Ibi) and mother has (Iai).
(b). If this man is father of child then the genotypes of the parents will be as discussed above i.e
Father- Ibi
Mother-Iai
(c). If the man's genotype is IbIb then he cant be the father because he will have gamates as Ib and Ib, so regardless of mother's genotype he cant be the father because he mist have one gamate as i that is for blood group O.
(d). If the man has blood group AB then he will have genotype and IaIb and gamates will be Ia and Ib ,then he cant be the father because again he is missing that allele i for blood group O.
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