Question 3 2 points Save Answer Consider the signaling pathway depicted below, w

Question

Question 3 2 points Save Answer Consider the signaling pathway depicted below, which involves two different receptors. Assume that a protein is active only when it is activated but not inhibited by its upstream signaling molecules. Activation and inhibition are indicated by normal and blunt arrows, respectively. Under which of the following conditions is target-gene expression induced Signal Signal 2 GPCR RTK G protein Kinase Adaptor Second messenger Binding protein -O- -O Transcr ption regulator Gene expression and cellular response OA. In the presence of either or both signals (1 or ) B. Only in the presence of signal 2 but not signal 1 OC.Only in the presence of both signals (1 and 2) OD. In the presence of either signal but not both of them E. Only in the absence of both signals

Explanation / Answer

D is correct. Target gene expression induced in the presence of either signal but not both of them because adaptor of signal 1is inhibitor of binding protein of signal 2 and kinase of signal 2 is inhibitor of enzyme of Singal 1 . These two inhibition ultimately leads to gene supression.

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