Homework 1. 2. Give the function of each of the following (a) active site of an

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Homework 1. 2. Give the function of each of the following (a) active site of an enzyme (b) coenzyme (c) allosteric site (5 points) Why is ATP able to serve as an important link between exergonic and endergonic reactions? (5 points) You are doing an experiment in which you are measuring the rate at which succinic acid is converted to fumaric acid by the enzyme succinic dehydrogenase. You decide to add a little malonic acid to make things more interesting. You observe that the reaction rate slows markedly and conclude that malonic acid must be acting as an inhibitor. Design an experiment that will help you decide if malonic acid ia acting as a competitive inhibitor or a noncompetitive inhibitor. (10 points) 3.

Explanation / Answer

1. a) active site of the enzyme binds with the substrates according to a lock and key fit. Inside the active site the substrate forms bonds with amino acids inside it to lower down the activation energy for the paticular reaction to accelerate the reaction.

b) coenzymes bind to different enzymes and help in catalysis.

c) allosteric site is a site on the enzyme to which the small molecules bind to and regulate the activity of the enzymes.

2. During an exergonic reaction, the energy is released in the form of ATP molecules. However, in an endergonic reaction energy is consumed in the form of ATP hydolyses

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