A newly discovered species of mouse completely lacks any form of recombinase. Pr

Question

A newly discovered species of mouse completely lacks any form of recombinase. Protein analysis has shown this species contains at least 100,000 different secreted immunoglobulins of unique sequence. Based on your knowledge that a typical immunoglobulin has a mass of about 400 kDa and that each amino acid has an average mass of 100 Da, you make the startling conclusion that species has dedicated how many base pairs of its genome just to generate immunoglobulins?

A.100,000

B.400,000

C.12,000,000

D.400,000,000

E.1,200,000,000

Explanation / Answer

E.1,200,000,000

a typical immunoglobulin has a mass of about 400 kDa or 400,000Da

Now, each amino acid has an avarage mass of 100 Da.

Thus there are 400,000/100= 4000 amino acids are present in each immunoglobulin.

as each amino acid is comprised of 3 bases, there are 4000 X 3= 12,000 bases are present in each amino acid.

Now, there are 100,000 secreted immunoglobulin are present, thus in total 100, 000 X 12,000 =1,200,000,000 base pairs of genome generated the immunoglobulins.

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