7. Which of the follawing functions are associated with CD40-CD40L interactions?

Question

7. Which of the follawing functions are associated with CD40-CD40L interactions? A. It induces NF-kB activation B. It induces B cells to undergo isatype class switching C. It licenses Dendritic Cells to activate naive CDB T cells D. Together with IFNy stimulation, it promotes classical activation of macrophages E. All of the above 8. Which of the fallowing functions is NOT associated with an alternatively activated macraphage? A. They promate wound repair and collagen synthesis B. They are found in tumars C. They kill intracellular pathogens D. They are activated in a Th2 environment E. They have high expression of the enzyme Arginase . Which of the fallowing Target Cells (TC) CANNOT be killed by a CTL? A. A TC with no FAS B. A TC with no FASL C. A TC with no Caspase 3 D. A TC with na Caspase 8 E. A TC with no IFNy-receptor 10. Which of the following cytokine and transcription factor combinations is required for a naive ThO CD4+ T cell to differentiate into a Th17 cell? A. IFNy, RORyt, T bet B. IL-4, STAT4, T bet C. IL-6, STAT3, TGFB, RORyt D. IFNy, IL-12, STAT4, T bet E. IL-4, STAT6, GATA3

Explanation / Answer

7) E- All Of the Above

8) C : alternatively activated microphages do not kill intracellular pathogens, that is the function of M0 or classicaly activated microphages.

3) F - A,B and C : Express Complement receptors ( CR1,2,3), Capture Antigens and reside in Lymph node follicles.

5) B Dark Zone

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