Question 11 In DNA replication, the helix is opened and untwisted by: DNA primas

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Question 11

In DNA replication, the helix is opened and untwisted by:

DNA primase.

single-strand-binding proteins.

DNA ligase.

helicase.

DNA polymerase.

1 points

Question 12

_______ are tandemly repeated DNA sequences located at the ends of eukaryotic chromosomes.

Replication bubbles

Telomeres

Nucleosomes

Licensing factors

Holliday junctions

1 points

Question 13

All DNA polymerases synthesize new DNA by adding nucleotides to the _____ of the growing DNA chain.

3' OH

5' OH

3' phosphate

5' phosphate

nitrogenous base

1 points

Question 14

If the sequence of one strand of DNA is 5' GCTAGCGTCG 3', what is the sequence of the complementary DNA strand?

3' GCTAGCGTCG 5'

5' GCTGCGATCG 3'

3' CGATCGCAGC 5'

5' CGATCGCAGC 3'

5' CGAUCGCAGC 3'

1 points

Question 15

Which of the following is NOT required for transcription in prokaryotes?

Sigma factor

RNA primers

DNA template

RNA polymerase

Promoter

1 points

Question 16

If the sequence of the non-template strand of DNA is 5' CATGCTATTGC 3', the mRNA sequence will be:

5' GUACGAUAACG 3'

5' CAUGCUAUUGC 3'

5' GCAAUAGCAUG 3'

5' CGUUAUCGUAC 3'

None of the above.

1 points

Question 17

Which of the following is found on the primary product of transcription but not on a mature mRNA molecule in eukaryotes?

Start codon

Stop codon

Exons

Introns

All of the above are found on a mature mRNA transcript.

1 points

Question 18

Which of the following occur in both eukaryotic and bacterial transcription?

The addition of a 5' cap.

Addition of the poly(A) tail.

Promoter.

Removal of introns.

All of the above.

1 points

Question 19

In rho-dependent transcription termination:

the formation of a hairpin in the transcribed mRNA causes RNA polymerase to pause, facilitating termination.

rho binds the mRNA, and when it makes contact with RNA polymerase, it assists with the removal of the mRNA from the DNA template.

the rho factor binds to the -10 consensus sequence located in the promoter region to terminate transcription.

a site within the poly(A) tail is cleaved which signals termination.

the 3' untranslated region (3' UTR) is synthesized.

1 points

Question 20

If the sequence of an mRNA molecule is 5' GGCAUCGACG 3', what is the sequence of the nontemplate strand of DNA?

5' GGCATCGACG 3'

3' GGCATCGACG 5'

5' CCGTAGCTGC 3'

3' CCGTAGCTGC 5'

3' CGTCGATGCC 5'

DNA primase.

single-strand-binding proteins.

DNA ligase.

helicase.

DNA polymerase.

Explanation / Answer

11. Helicase enzyme involves in the unwinding of the DNA during the replication.

12. Telomers are the tandomly repeated sequences which are present at the end of the eukaryotic chromosome. These sequences protects chromosomal fusion by the neighbouring chromosomes.

13. 3'OH Of the growing chain.

14. 3'CGATCGCAGC5'

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