Unlike signal transduction in many other sensory receptors, signal transduction
ID: 214290 • Letter: U
Question
Unlike signal transduction in many other sensory receptors, signal transduction in rods?
involves a second messenger.
Suppose a mutation greatly increases the affinity of a rod’s sodium channels for cGMP, such that once cGMP binds to a channel, it remains bound for much longer than normal. What would be the effect of this mutation on the rod’s sodium channels?
results in hyperpolarization of the sensory cell. does not involve the participation of a G protein. takes place entirely in the plasma membrane.involves a second messenger.
Suppose a mutation greatly increases the affinity of a rod’s sodium channels for cGMP, such that once cGMP binds to a channel, it remains bound for much longer than normal. What would be the effect of this mutation on the rod’s sodium channels?
The sodium channels would open and close randomly, regardless of the presence of light. The sodium channels would remain closed in the light and the dark, even when cGMP decreases after light stimulation. The sodium channels would remain open in the dark and close rapidly in the light. The sodium channels would remain open longer, even when cGMP decreases after light stimulation.Explanation / Answer
Unlike signal transduction in many other sensory receptos, signal transduction in rods?
Ans. Option 1: Results in hyperpolarization of the sensory cell
Explanation: Signal transduction in rods (Phototransduction) involves Gprotein cells. So first option is wrong which says that it does not involve participation of a G protein. 3rd option is also wrong as phototransduction cascade entirely does not occur in rods. Signal transduction involves secondary messengers in rods as well as other sensory receptors also, hence, this is also not correct choice
Suppose a mutation greatly increases the affinity of a rod’s sodium channels for cGMP, such that once cGMP binds to a channel, it remains bound for much longer than normal. What would be the effect of this mutation on the rod’s sodium channels?
Ans. The sodium channels would remain open longer, even when cGMP decreases after light stimulation.
As long as cGMP is present Sodium channels remain open, as the given mutation increases the affinity of Sodium channel, the channels remain open for longer period
Remaining options mentions about the open and closure of sodium channels which will not occur if cGMP affinity for Sodium channels increases
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