There is a movement to recreate the Woolly Mammoth through genome engineering. I

Question

There is a movement to recreate the Woolly Mammoth through genome engineering. It is proposed to be done by manipulating the genome of elephants. Genome analysis can provide clues regarding how this might most efficaciously done. BLAST the Mammuthus primigenius mitochondria gene cytochrome B YP 398766.1 against Database: Reference proteins (refseq_protein) limiting to Organism: Elephantidae (taxid: 9780) AND excluding Mammuthus (taxid:37348). Looking at the BLAST results (select all that apply): No taxid members have related cytochrome B sequences. Judging from highest scores (Max and Total) and Identity, the Woolly Mammoth cytochrome B sequence is more closely related to American Mastodons (Mammut americanum) than to modern elephants (Loxodonta africand) Judging from highest scores (Max and Total) and Identity African Savanna elephants (Loxodonta africana) may be a slightly better choice than Indian Elephants (Elephas maximus) due to greater similarity Judging from the most significant Blast hits and percent Identity for cytochrome b, African savanna elephants (Loxodonata africana) and Indian elephants African forest elephants (Loxodonta cyclotis) both be suitable species to recreate the Mammoth

Explanation / Answer

Judging from highest scores (max and total) and identity, african savanna elephants may be slightly better choice than indian elephants due to greater similarity.

African elephants share a 98% identity to mammoths than indian elephants which has a 97% identity. Hence, the africa n elephants are more similar to mammoths than indian elephants.

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