7. Explain why DNAdenatures Cerparatcs Inte two strands) at pH> 11 Model 2 The C

Question

7. Explain why DNAdenatures Cerparatcs Inte two strands) at pH> 11 Model 2 The Central Dogma of Molecular Blology DNA s senso -T-c-T-C-C-A-C-G-A s antl-sense mRNA 5. -A-G-A-G-G-U-G-C-U-3( tRNAs 3' U-C-U-c-C-A-C-G-A 5 | Arginine Glycine Alanine Protein -Arginine -Glycine - Alanine- 8. Place the terms transcriplon, translation, codons and antlcodons in the appropriate boxes of Model 2, above 9. From which strand is the mRNA synthesized, the sense strand or the antisense strand of the DNA? 10. How does the sense strand of the DNA differ from the structure of the mRNA? How is it alike? 11. How many consecutive nucleotides code for a single amino acid? 12 In which biopolymer (DNA, mRNA, IRNA or protein) would a mutation need to be located in order to be heritable and why?

Explanation / Answer

Ans.7

At high pH i.e., 11 the solution is rich in hydroxide ions, and these negatively-charged ions interact with hydrogen ions in the base pairs in DNA. This process disrupts the hydrogen bonding that holds the two DNA strands together, causing them to separate.

Ans.8

uppermost box - Transcription i.e., synthesis of mRNA from DNA

second box - Codons i.e.,three nitrogen bases in a row on mRNA that code for a amino acid.

third box - anticodons i.e.,three-base sequences on tRNA which are complementary to codons

lowermost box - Translation i.e., synthesis of protein from mRNA.

Ans. 9

from the antisense strand of the DNA mRNA is synthesized

Ans.10

sense strand of the DNA has thymine instead of uracil but the rest of the bases are same.

Ans. 11

3

Ans.12

a mutation needs to be located on DNA in order to be heritable because it is the DNA which is transferred from one genearation to the next generation and not the mRNA, tRNA or protein.

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