Crifical Thinking Questions ONA Strands 1. Which bases pair with one another in

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Crifical Thinking Questions ONA Strands 1. Which bases pair with one another in DNA Model 1 Clasify each base as either purine Sugarphosphate comelementarybackbon pyrimidine. How many hydrogen bonds are ackbonese pairing formed between cach of these pairs? 2. What is the name of the augar found in DNA 3. What is the name of the menomer that makes 3 up the DNA polymer? 4. Are the complementary strands parallel or an- tiparallel? How do you know? 5. List the intermolecular forces that are important in stablizing the double helical structure. Indicate with a "which force(s) are more important. Do not dwell on this 6. Prior to the elucidation of the structure of DNA by Watson and Crick in 1953, Chargaff noted that the total amount of A + G in DNA is equal to the total amount of C+ T, regardless of the source of the Explain the structural basis of this observation, knowing what we know now about the structure of DNA. Foundations of Biochemistry

Explanation / Answer

1. In DNA, Adenine (A) pairs with thymine (T) and guanine pairs with cytosine (C). Adenine and guanine are purines and thymine and cytosine are pyrimidines.

2. Sugar Deoxyribose is found in DNA .

3. Nucleotides are the monomers that make up DNA polymer.

4. Complementary strands are antiparallel because one strand runs in 5'-3' direction and other strand runs in 3'-5' direction.

5. Hydrogen bonds, hydrophobic interactions and vander waals interactions stabilize DNA helix. Hydrogen bonds are important to stabilize the DNA helix.

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