Why would phage need to synthesize more cI repressor during establishment of lys
ID: 211229 • Letter: W
Question
Why would phage need to synthesize more cI repressor during establishment of lysogeny, early in infection, rather than in maintenance of the lysogenic state?
A. The genes of phage multiplication are repressed by proteolytic cleavage, which is an irreversible process that is induced by the cI repressor, so once the majority has been degraded, a lower level of cI will suffice.
B. The genes of phage multiplication are repressed by a cascade of different co-repressors, which are induced by the original cI repressor, so once they are activated, a lower level of cI will suffice.
C. CI and cro genes compete to establish the phage lifestyle, so a large amount of cI repressor is needed to overcome cro activity, but afterward a lower level of cI will suffice.
D. CI acts as a transcriptional activator of genes that promote lysogeny, so after they are activated and overcome phage multiplication genes a lower level of cI will suffice.
Explanation / Answer
Ans. B
The genes of phage multiplication are repressed by a cascade of different co-repressors, which are induced by the original cI repressor, so once they are activated, a lower level of cI will suffice.
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