WINTER QUARTER 2018 EXAM 4 (100 points) 18. Which of the following is NOT a feat
ID: 211132 • Letter: W
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WINTER QUARTER 2018 EXAM 4 (100 points) 18. Which of the following is NOT a feature of RNA? a. b. c. d. e. RNA is single stranded Uracil is found in RNA in place of thymine RNA has a 3' OH group instead of an H RNA forms complex secondary structure via self-complementation All of the above are features of RNA 19. RNA synthesis is always and to the strand of DNA. a. Complimentary, parallel, non-template b. Complimentary, anti-parallel, non-template c Complimentary, anti-parallel, template d. Non-complimentary, parallel, template e. Complimentary, parallel, template 20. A bacterial RNA polymerase complex is capable of binding to DNA but randomly initiates transcription. Which subunit of the RNA polymerase holoenzyme is most likely missing? a. Sigma b. Alpha c. Beta d. TBP e. TFIID 21. For the basal transcription of MOST eukaryotic mRNAs, the is the MOST important region of the core promoter. This site is recognized by a critical component of TFlID a. TFIIB recognition element b. Initiator element c. Downstream core promoter element d. Regulatory promoter e. TATA box 22. Use the figure below to answer the following question. Assume that the indicated RNA transcript has a highly structured 3'UTR (not shown) immediately upstream of the stem-loop sequence. Which mechanism of transcriptional termination is most likely to be involved? hairpin oop a. Rho-dependent b. Rho-independent c. Rat1-dependent d. Rat1-independent e. It is impossible to tell from the picture stem poly-U transcription DNA . Many genes are 23. In prokaryotes, transcription and translation are a. Coupled, monocistronic b. Coupled, polycistronic c. Spatially separated, polycistronic d. Spatially separated, monocistronic e. Temporally separated, polycistronic 4Explanation / Answer
Answer for question number 18 : The correct option is E ( all of the above are the features of RNA)
Answer for question number 19 : RNA synthesis is always COMPLIMENTARY and ANTI PARALLEL to the TEMPLATE strand.
Answer for question number 20 : The correct option is A (sigma factor)
Explanation : Sigma subunit plays an important role in directing the RNA polymerase to bind to specific sites on DNA molecules called promoters and also reduces the affinity of RNAP for non specific sites on DNA during transcription.
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