You are examining linkage between the genes that contribute to vampire teeth mor

Question

You are examining linkage between the genes that contribute to vampire teeth morphology L_long teeth Il short teeth You cross a true breeding vampire that has long, yellow teeth that have a normal amount of dentin with a true breeding vampire that has short, white teeth that lack sufficient amounts of dentin. You then test cross one of the F1 offspring. The number and phenotypes of the offspring are below (apparently they are very fecund!). Y-yellow teeth yy white teeth D_sufficient dentin (dentin +) dd lacks sufficient dentin (dentin -) Phenotype long, yellow, dentin + short, white, dentin - long, yellow, dentin short, white, dentin+ long, white, dentin + short, yellow, dentin - long, white, dentin - short, yellow, dentin+ Counts 56 61 23 19 210 189 What is the degree of interference between the loci? a, 4096 b. 55% C. 30% d. 45%

Explanation / Answer

The most abundant phenotypes are the parental types they are long,white,dentin- and short,yellow,dentin+

Least frequent are the double crossover genotypes they are long,white,dentin+ and short,yellow,dentin-

The linkage distance should be calculated between the long yellow dentin+ and short white dentin- which is calculated as (56+61+3+2/563)= 0.2

563 i the total no. of phenotypes

And also for long yellow dentin- and short white dentin+ is (23+19+3+2/563)=0.08

The recombination frequency is 100×(0.2×0.08)= 1.6

The interfernce = 1- observed double recombinants

expected double recombinants

Ovserved are 8 and expected are more than the observed.

Hence a would be the answer

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