1. Which sequence of events leads to protein secretion? Events: 1. Glycosylation
ID: 210424 • Letter: 1
Question
1. Which sequence of events leads to protein secretion?
Events:
1. Glycosylation and tagging in Golgi apparatus.
2. Folding and glycosylation in rough endoplasmic reticulum.
3. Fusion of secretory vesicles with plasma membrane and release of secreted proteins.
4. Translocation into rough endoplasmic reticulum.
5. Transfer from rough endoplasmic reticulum to Golgi apparatus in transport vesicles.
6. Export from Golgi apparatus in secretory vesicles.
7. Synthesis by ribosomes.
Select one:
a. 4, 7, 1, 5, 3, 2, 6
b. 2, 7, 3, 5, 4, 1, 6
c. 7, 4, 2, 5, 1, 6, 3
d. 2, 3, 6, 7, 4, 5, 1
e. 2, 5, 3, 7, 6, 4, 1
2. Which property of phospholipids is responsible for the formation of phospholipid bilayers?
Select one:
a. Phospholipids are hydrophilic
b. Phospholipids are hydrophobic
c. Phospholipids are amphiphilic
d. Phospholipids are positively charged
e. Phospholipids are negatively charged
3. In the presence of oxygen, all cells synthesize ATP via the process of glycolysis. Many cells also can metabolize pyruvate if oxygen is not present, via the process of:
Select one:
a. fermentation
b. aerobic respiration
c. oxidative phosphorylation
d. electron transport
e. photophosphorylation
4. In aerobic respiration carbohydrates are ultimately broken down into:
Select one:
a. acetyl-CoA
b. CO2
c. O2
d. H2O
e. heat
5. Identify the statement about meiosis that is incorrect
Select one:
a. Pairing of homologous chromosomes
b. Four haploid cells are formed
c. At the end of meiosis the number of chromosomes are reduced to half
d. Two cycle of DNA replication occurs
6. What is the mitotic spindle made of?
Select one:
a. Mitosis
b. Microtubules
c. Chromosomes
d. The nuclear envelope
e. Chiasmata
7. Products of glycolysis include:
Select one:
a. pyruvate
b. ATP
c. NADH
d. all of the above
8. Which of the following is not a characteristic of enzymes?
Select one:
a. They change shape when they bind their substrates
b. They can catalyze reactions in both forward and reverse directions
c. Their activity is sensitive to changes in temperature
d. They are always active on more than one kind of substrate
e. They may have more than one binding site
9. What does a target cell require to respond to an extracellular signal molecule?
Select one:
a. Access to the signal molecule
b. The presence of an appropriate receptor for the signal molecule
c. Appropriate intracellular signaling pathways
d. All of the above
10. Which of the events listed below is not observed during mitosis?
Select one:
a. Chromatin condensation
b. Movement of centrioles to opposite poles
c. Appearance of chromosomes with two chromatids joined together at the centromere.
d. Crossing over
11. Meiosis results in:
Select one:
a. Production of gametes
b. Reduction in the number of chromosomes
c. Introduction of variation
d. all of the above
12. Complete the following sentence: "Cyclin levels __________ during cell cycle whereas cyclin-dependent kinase (CDK) levels __________. Progression through cell cycle results from the formation of __________ complexes, within which __________ is activated through phosphorylation."
Select one:
a. remain constant, vary, cyclin-CDK, CDK
b. remain constant, vary, CDK-CDK, CDK
c. vary, remain constant, cyclin-CDK, CDK
d. vary, remain constant, cyclin-cyclin, cyclin
e. vary, remain constant, cyclin-CDK, cyclin
13. Two true breeding parents are crossed similar to Mendel's P generation. A tall plant is crossed with a short plant. What is the expected outcome for the F1 generation?
Select one:
a. all short
b. all tall
c. all medium height
d. half tall, half short
14. Cyanide is a poison that binds to the active site of the enzyme cytochrome c and prevents its activity. Cyanide is a(n):
Select one:
a. Prosthetic group
b. Cofactor
c. Coenzyme
d. Inhibitor
e. Reverse regulator
15. Complete the following sentence: "A competitive inhibitor competes with substrate binding to the __________ site, generally by also binding to this site; its effect on reaction rate becomes neglectable when the concentration of __________ is sufficiently high compared to the concentration of __________."
Select one:
a. active, inhibitor, substrate
b. active, substrate, product
c. active, substrate, inhibitor
d. allosteric, inhibitor, substrate
e. allosteric, substrate, inhibitor
16. As protons flow through the ______, energy is released and exploited to combine ADP and inorganic phosphate to form ATP.
Select one:
a. electron transport chain
b. outer mitochondrial membrane
c. cytochrome oxidase
d. ATP synthase
e. NADH
17. The high concentration of protons in the inner mitochondrial space relative to the mitochondrial matrix represent
Select one:
a. magnetic energy
b. kinetic energy
c. potential energy
d. photonic energy
e. none of the above
18. Fill in the following equation: ATP + ___ ADP + ___
Select one:
a. H2O, Pi
b. H2O + free energy, Pi
c. free energy, Pi + H2O
d. H2O, Pi + free energy
e. free energy, Pi
19. Which of the following molecules can pass through the plasma membrane by simple diffusion? Check all that apply.
Select one or more:
a. Simple sugars
b. Sodium ions
c. Fat-soluble drugs
d. Dioxygen
e. Fat-soluble vitamins
20. During anaphase-I of meiosis:
Select one:
a. Homologous chromosomes separate
b. Non-homologous autosomes separate
c. Sister chromatids separate
d. Non-sister chromatids separate
Thank you
Explanation / Answer
1. The answer is option C
Firstly protein is synthesized by ribosomes.
Then it is translocated into the ER lumen.
Then folding and glycosylation takes place in ER.
Now protein is transferred to golgi.
There is is further modified.
Now protein is exported from golgi to secretory vesicles.
Finally secretory vesicle is fused with plasma membrane and the protein is secreted.
2. The answer is option-C
Phospholipids are amphiphiic. Phospholipid head is hydrophilic and tail portion is hydrophobic. So it is amphiphiic molecule.
3. The answer is- A
In absence of oxygen fermentation takes place. Pyruvate produced from glycolysis is metabolised in fermentation.
4. The answer is- B
In aerobic respiration carbohydrates finally generates CO2.
5. In this question all the options about meiosis is correct. All 4 options are correct.
6. The answer is B- microtubules
7. The answer is D -all of the above
8. The answer is option -D
9. The answer is option- D -all the above
10. The answer is option- D.
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