Name CHEM 363 Homework Set #5 ers 6 and 13 (worth 20 points) Due Thunday, March

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Name CHEM 363 Homework Set #5 ers 6 and 13 (worth 20 points) Due Thunday, March 15, 2018 1. 3 pts) Briefly, compare and contrast globular and fihrous protcis 2 (3 pts) Proteins can be undolded, or denatured, by agents that alter the balance of weak soncovalent forces that maintain the mative conformation. How would the Sollowing agents cause a prolcin to denature? Be specific aboue the type of imermolocular foeces that would be affected a Heat b. ph c. amphiphilie detergents d. reducing agents such as 2-mercaptoethanol (HSCH CHO) 3. (1 pt) What information does a Ramachandran diagram provide? 4. (3 pts) Choose one of the following secondary structures (a-helix, p-pleated sheet, p- tum) that we discussed in class. Draw a diagram that shows how bhydrogen bonds stabilize this structure.

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Fibrous proteins Globular proteins Do not have a tertiary structure Have a tertiary structure.Quaternary may or may not be present. Insoluble in water Soluble in water to form a colloidal solution These perform structural function in the body These perform metabolic function in the body Long fibres or sheet like in shape shape is spherical the length of the polypeptide chain may vary in two samples of the same fibrous proteins the length of the polypeptide chain is always the same in two samples of the same fibrous proteins examples: keratin, collagen examples:albumin, serum globulin

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