Date 7. In order to generate the most amount of energy during the oxidation of g

Question

Date 7. In order to generate the most amount of energy during the oxidation of glucose, which of the following has to take place? A. Direct and complete oxidation of glucose B. Compartmentalized metabolism in a stepwise fashion C. Stepwise metabolism with energy investment at every step D. Reversible metabolism with no heat loss 8. Which of the following enzymes is the rate limiting step in oxidative phosphorylation? A. Pyruvate Kinase B. Phosphoglycerate Kinase C. Hexokinase D. Aldolase 9. During glycolysis, which of the following enzymes are responsible for the generation of the relevant activated carrier? A. Aldolase, phosphoglucose isomerase B. Enolase, phosphoglycerate mutase C. Glyceraldehyde 3-phosphate dehydrogenase D. Phosphoglucose isomerase 10. During the preparatory phase, which of the following best describes the produces that are generated? A. Acetyl-CoA, ATP and NADH B. CO2, Acetyl-CoA C. NADH, ATP, FADH2 D. Pyruvate, ATP 11. During the citric acid cycle, the enzyme that catalyzes the conversion of Succiny-CoA to Succinate is? A. Succinyl-CoA synthetase B. Succinate reductase C. Isocitrate dehydrogenase D. Fumarase 12. An investigator is synthesizing a small molecule compound that inhibits the efficacy of Maleate by 50%. What is the most likely predicted ATP deficit in the cell? A. 23 B. 36 C. 8 D. 16 13. The final metabolite generated by glycolysis is? A. Water B. ATP

Explanation / Answer

Question 7

Direct and complete oxidation of glucose is required to generate maximum amount of energy during oxidation of glucose. In aerobic respiration, complete oxidation of glucose occurs which results in the release of 686 kilocalorie of energy whereas anaerobic respiration involves incomplete oxidation of glucose which results in the release of only 28 kilocalorie of energy.

Question 8

Both pyruvate kinase and hexokinase are the major sites of regulation of glycolysis.

Question 9

During glycolysis, Glyceraldehyde 3-phosphate dehydrogenase enzyme is used to convert Glyceraldehyde 3-phosphate to 1,3 - biphosphoglycerate. In the process NAD is converted to NADH which is resposible for the generation of relevant activated carrier.

Question 10

During the preparatory phase of glycolysis, two ADP moleculews are formed from two ATP molecules. But the entire process of glycolysis results in the release of two pyruvate molecules, two NADH, two hydrogen ions and two ATP molecules.

Question 11

Succinyl-CoA synthetase catalyses the conversion of Succinyl CoA to siccinate in the citric acid cycle.

Question 13

The final metabolites generated by glycolysis are pyruvate, NADH, ATP and hydrogen ions

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